| Autor: |
Papadopoulos AJ; Department of Physics, The City College of the City University of New York, NY 10031, USA., Zhadin NN, Steinberg ML, Alfano RR |
| Jazyk: |
angličtina |
| Zdroj: |
Cancer biochemistry biophysics [Cancer Biochem Biophys] 1999 Jul; Vol. 17 (1-2), pp. 13-23. |
| Abstrakt: |
Native fluorescence emission and excitation spectra of SV40 infected human keratinocytes, A431 and SCC324 carcinoma cells, and normal human keratinocytes were measured and compared. A difference in the intracellular metabolic state of NADH was found between the normal cells and the cancer or virus-transformed cells. The observed difference, namely an increased proportion of bound, mitochondrial NADH in the cancer and virus-infected cells, manifests as a blue spectral shift in the emission spectra. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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