[Systemic enzyme therapy in chronic glomerulonephritis].

Autor: Siniachenko OV, Kovalenko VN, Mukhin IV, Ignatenko GA, Terzov AI
Jazyk: ruština
Zdroj: Terapevticheskii arkhiv [Ter Arkh] 2000; Vol. 72 (2), pp. 46-8.
Abstrakt: Aim: To try polyenzyme drug vobenzim in chronic glomerulonephritis (CGN).
Materials and Methods: 174 CGN patients were randomized into 2 groups. The study group of 39 patients received conventional pathogenetic treatment plus vobenzim (initial dose 18-24, maintenance 12-15 dragees a day). Control group of 135 patients were given only pathogenetic therapy. 67 patients appeared ineligible.
Results: 3-6 months after the treatment the response was seen in 61.5% patients of the study and 17.8% patients of the control group. Side effects of vobenzim in CGN treatment were absent.
Conclusion: Enzyme therapy with vobenzim in CGN is safe and effective.
Databáze: MEDLINE