Autor: |
Spanos PK, Payne WS, Ivins JC, Pritchard DJ |
Jazyk: |
angličtina |
Zdroj: |
The Journal of bone and joint surgery. American volume [J Bone Joint Surg Am] 1976 Jul; Vol. 58 (5), pp. 624-8. |
Abstrakt: |
A retrospective analysis of thirty patients who underwent pulmonary resection for metastatic osteosarcoma over a twenty-eight-year period revealed that most were young males with previous amputations for primary lesions of the lower extremity. In each, one to four thoracotomies had been performed, for a total of fifty-two chest operations with resection of 124 pulmonary metastatic lesions. At last follow-up, eleven of the thirty patients were alive and free of disease. At five years 28 per cent had survived: three of them were alive at more than nine years, and one was alive at nearly twenty years. Adverse survival factors identified were short tumor-free interval and multicentricity of pulmonary metastases. Long-term survival was associated with a tumor-free interval of more than two years and one to four thoracotomies at which few foci were present. As a group, patients selected for lung resection had significantly longer suvival than did patients whose pulmonary metastasis was untreated. |
Databáze: |
MEDLINE |
Externí odkaz: |
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