Discovery of orally active nonpeptide vitronectin receptor antagonists based on a 2-benzazepine Gly-Asp mimetic.
Autor: | Miller WH; Research & Development Division, SmithKline Beecham Pharmaceuticals, Collegeville, PA 19426-0989, USA. williamvhvmiller@sbphrd.com, Alberts DP, Bhatnagar PK, Bondinell WE, Callahan JF, Calvo RR, Cousins RD, Erhard KF, Heerding DA, Keenan RM, Kwon C, Manley PJ, Newlander KA, Ross ST, Samanen JM, Uzinskas IN, Venslavsky JW, Yuan CC, Haltiwanger RC, Gowen M, Hwang SM, James IE, Lark MW, Rieman DJ, Stroup GB, Azzarano LM, Salyers KL, Smith BR, Ward KW, Johanson KO, Huffman WF |
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Jazyk: | angličtina |
Zdroj: | Journal of medicinal chemistry [J Med Chem] 2000 Jan 13; Vol. 43 (1), pp. 22-6. |
DOI: | 10.1021/jm990446u |
Databáze: | MEDLINE |
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