Selective plasma hydrolysis of glucocorticoid gamma-lactones and cyclic carbonates by the enzyme paraoxonase: an ideal plasma inactivation mechanism.

Autor: Biggadike K; Medicinal Chemistry, Enzyme Pharmacology, Biomet Doscovery and Potein Science Units, Glaxo Wellcome Research and Development, Medicines Research Centre, Hertsfordshire, UK. kb0903@ggr.co.uk, Angell RM, Burgess CM, Farrell RM, Hancock AP, Harker AJ, Irving WR, Ioannou C, Procopiou PA, Shaw RE, Solanke YE, Singh OM, Snowden MA, Stubbs RJ, Walton S, Weston HE
Jazyk: angličtina
Zdroj: Journal of medicinal chemistry [J Med Chem] 2000 Jan 13; Vol. 43 (1), pp. 19-21.
DOI: 10.1021/jm990436t
Databáze: MEDLINE