| Autor: |
Hartman CP, Fulk GE, Andrews AW |
| Jazyk: |
angličtina |
| Zdroj: |
Mutation research [Mutat Res] 1978 Nov; Vol. 58 (2-3), pp. 125-32. |
| DOI: |
10.1016/0165-1218(78)90001-0 |
| Abstrakt: |
The azo reductase activity of a cell-free extract of Fusobacterium sp. 2 is characterized using trypan blue as a substrate. Either chemical reduction of this dye with sodium hydrosulfite or reduction by the cell-free extract produces a mutagenic product, o-tolidine. The o-tolidine is mutagenic in the Ames Salmonella/mammalian-microsome mutagenicity test when activated by a rat liver S9 preparation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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