Autor: |
Monacelidze DR; Institute of Physics, Georgian Academy of Sciences, Tbilisi, Georgia., Madzhagaladze GV, Bakradze NG, Birkaia VG, Sapozhnikova NA, Asatiani NV |
Jazyk: |
ruština |
Zdroj: |
Biofizika [Biofizika] 1999 Sep-Oct; Vol. 44 (5), pp. 910-3. |
Abstrakt: |
It was shown by the method of differential scanning microcalorimetry that an additional peak, at about 57 degrees C appears on heat absorption curves of the whole spleen tissue and cells of BalB/c mouse injected with Rausher virus. It is supposed that this peak is due to the melting of AT-rich regions of internucleosomal DNA in chromatin fibers of tumor cells, which results from the partial loss of proteins or the modification of H1 histone. |
Databáze: |
MEDLINE |
Externí odkaz: |
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