| Autor: |
Vu CB; ARIAD Pharmaceuticals, Inc., Cambridge MA 02139-4234, USA., Corpuz EG, Pradeepan SG, Violette S, Bartlett C, Sawyer TK |
| Jazyk: |
angličtina |
| Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 1999 Oct 18; Vol. 9 (20), pp. 3009-14. |
| DOI: |
10.1016/s0960-894x(99)00524-7 |
| Abstrakt: |
The synthesis of a series of 1,2,4-oxadiazole analogs is discussed along with their ZAP-70 SH2 inhibitory activity. The tyrosine moiety in the original series has been replaced with nonpeptidic functional groups without a substantial loss of binding affinity. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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