| Autor: |
Drew ML; Department of Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843, USA., Meyers-Wallen VN, Acland GM, Guyer CL, Steinheimer DN |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 1999 Oct 15; Vol. 215 (8), pp. 1134-9. |
| Abstrakt: |
Multiple congenital abnormalities of the external genitalia consistent with XX sex reversal were detected in a juvenile llama. The llama had a typical female karyotype (74, XX) and did not have a Y chromosome, but a minute chromosome was detected. To determine whether a piece of Y chromosome containing the Sry gene might be located in a small translocation, DNA analysis by polymerase chain reaction was performed; the Sry gene was not detected. Histologic examination revealed ovarian tissue, whereas testicular tissue was not found. External genitalia were partially masculinized, indicating that the urogenital sinus, genital tubercle, and genital swellings had been exposed to androgens during development, although the dam had not received exogenous androgens. Testicular tissue in the ovaries may have been undetected or had regressed prior to birth, as has been reported in sex reversal in mice. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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