| Autor: |
Vriesema AJ; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands., Dankert J, Zaat SA |
| Jazyk: |
angličtina |
| Zdroj: |
Current microbiology [Curr Microbiol] 1999 Dec; Vol. 39 (6), pp. 321-0326. |
| DOI: |
10.1007/s002849900466 |
| Abstrakt: |
We aimed to identify transcription signal sequences from Streptococcus gordonii strain CH1 by random chromosomal cloning. Five genomic fragments from a Sau3A digest, which constitutively activated transcription of a promoterless spectinomycin resistance gene in this strain, were isolated and characterized. Additionally, one promoter fragment was isolated that was specifically activated under iron-limiting conditions. A sequence motif with similarity to the consensus for Fur-binding regulatory DNA sequences (Fur box) in Escherichia coli was detected within the putative promoter region. The open reading frame downstream of this region possibly encodes a transmembrane protein involved in iron uptake. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
Full text from SpringerLink