Development of a predictive statistical model for the analgesic activity of a family of imides.

Autor: Andricopulo AD; Departamento de Química, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Brazil., Yunes RA, Cechinel Filho V, Nunes RJ, Frazer JW, Cordes EH
Jazyk: angličtina
Zdroj: Die Pharmazie [Pharmazie] 1999 Sep; Vol. 54 (9), pp. 698-704.
Abstrakt: Quantitative structure-activity relationship (QSAR) studies were done with a family of cyclic imides. Promising efforts to create a QSAR model with substantial predictive power for the design of novel cyclic imides with improved analgesic activity are reported.
Databáze: MEDLINE