| Autor: |
Cunha RV; Disciplina de Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Rio de Janeiro, Brazil. rivaldoc@alanet.com.br, Schatzmayr HG, Miagostovich MP, Barbosa AM, Paiva FG, Miranda RM, Ramos CC, Coelho JC, dos Santos FB, Nogueira RM |
| Jazyk: |
angličtina |
| Zdroj: |
Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 1999 May-Jun; Vol. 93 (3), pp. 247-9. |
| DOI: |
10.1016/s0035-9203(99)90008-1 |
| Abstrakt: |
During 1997 a large dengue epidemic occurred in Rio Grande do Norte, a State in north-east Brazil. The co-circulation of dengue virus type 1 and dengue virus type 2 was demonstrated by virus isolation in Aedes albopictus clone C6/36 cell-line and by reverse transcriptase-polymerase chain reaction (RT-PCR). IgM capture enzyme-linked immunosorbent assay confirmed 52.3% of the 8105 studied cases and dengue antigen was demonstrated by immunohistochemical reaction on hepatocytes from 2 out of 5 fatal cases studied. Individual risk factors for development of dengue haemorrhagic fever/dengue shock syndrome, such as hypertension, diabetes mellitus and bronchial asthma, are discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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