| Autor: |
Hyrin VM; Kyiv Medical Academy of Postgraduate Education, Ministry of Public Health of Ukraine., Dziublyk IV, Trokhymenko OP, Koval'chuk VK |
| Jazyk: |
ukrajinština |
| Zdroj: |
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) [Mikrobiol Z] 1999 May-Jun; Vol. 61 (3), pp. 37-45. |
| Abstrakt: |
A new method of application of platinum macromolecular complex poly{hexacis[chloroamine aquaplatinum (II)]}-mu-deoxyribonucleate (MCP) as a cell cycle synchronization inductor has been developed. The process of some RNA-genome viruses reproduction in cell cultures synchronized by MCP was studied. It was shown that the amount of virus protection in such cultures under special conditions can be increased 100-350 times without increasing the cell substrate amount. The obtained results may be used in biotechnology to increase production of virus antigens and vaccines. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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