Autor: |
Ryder TR; Department of Chemistry, Parke-Davis Pharmaceutical Research, Ann Arbor, MI 48105, USA., Hu LY, Rafferty MF, Lotarski SM, Rock DM, Stoehr SJ, Taylor CP, Weber ML, Miljanich GP, Millerman E, Szoke BG |
Jazyk: |
angličtina |
Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 1999 Aug 16; Vol. 9 (16), pp. 2453-8. |
DOI: |
10.1016/s0960-894x(99)00405-9 |
Abstrakt: |
Selective N-Type Voltage Sensitive Calcium Channel (VSCC) antagonists have shown utility in several models of pain and ischemia. We report the structure-activity relationship at the proximal phenyl group in a series of non-peptidyl VSCC blockers. |
Databáze: |
MEDLINE |
Externí odkaz: |
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