| Autor: |
Johnson DA; Pharmaceutical Discovery Division, Ribi ImmunoChem Research, Inc., Hamilton, MT 59840, USA., Sowell CG, Johnson CL, Livesay MT, Keegan DS, Rhodes MJ, Ulrich JT, Ward JR, Cantrell JL, Brookshire VG |
| Jazyk: |
angličtina |
| Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 1999 Aug 02; Vol. 9 (15), pp. 2273-8. |
| DOI: |
10.1016/s0960-894x(99)00374-1 |
| Abstrakt: |
A novel series of acylated omega-aminoalkyl 2-amino-2-deoxy-4-phosphono-beta-D-glucopyranosides (aminoalkyl glucosaminide 4-phosphates) was synthesized and screened for immunostimulant activity. Several of these compounds enhance the production of tetanus toxoid-specific antibodies in mice and augment vaccine-induced cytotoxic T cells against EG.7-ova target cells. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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