Cup-to-disc ratio: ophthalmoscopy versus automated measurement in a general population: The Rotterdam Study.
| Autor: | Wolfs RC; Department of Ophthalmology, Erasmus University, Rotterdam, The Netherlands., Ramrattan RS, Hofman A, de Jong PT |
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| Jazyk: | angličtina |
| Zdroj: | Ophthalmology [Ophthalmology] 1999 Aug; Vol. 106 (8), pp. 1597-601. |
| DOI: | 10.1016/S0161-6420(99)90458-X |
| Abstrakt: | Objective: To determine the correlations between ophthalmoscopic estimations and the measurements with a semiautomated image-analysis device of the vertical cup-to-disc ratio (VCDR) in the human optic disc. Design: Population-based, cross-sectional study. Participants: All subjects 55 years of age and older from the population-based sample of 6777 ophthalmologically examined subjects from The Rotterdam Study of whom gradable optic disc transparencies of at least 1 eye and ophthalmoscopic data of the same eye were available. Main Outcome Measures: Ophthalmoscopic assessment of the VCDR and semiautomated measurement of the VCDR. Methods: Indirect and direct ophthalmoscopy were performed in mydriasis to assess the VCDR. Optic disc transparencies made with a simultaneous stereoscopic telecentric fundus camera were analyzed with a semiautomated measurement system (Topcon Imagenet). Results: In 5143 subjects, the mean ophthalmoscopic VCDR was 0.30 (standard error [SE], 0.0021; range, 0.00, 1.00) compared with a semiautomatically measured VCDR of 0.49 (SE, 0.0019; range, 0.04, 0.86; difference, 0.19; P < 0.0001). The overall correlation between both methods was moderate (correlation coefficient, 0.61; SE, 0.11) and lower in small optic discs. Semiautomated optic disc measurements correctly identified 76% of the glaucoma cases (as defined using visual field data and ophthalmoscopic data about the optic disc). Conclusion: Semiautomated measurements of the VCDR are larger than the ophthalmoscopic VCDR estimate with a moderate correlation. The interobserver variability using Imagenet was smaller compared with the ophthalmoscopic assessments, and Imagenet was better standardized, which is important for epidemiologic surveys and follow-up studies. |
| Databáze: | MEDLINE |
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