The combination paclitaxel, carboplatin and megestrol acetate is effective in women with recurrent uterine papillary serous adenocarcinoma.

Autor: Eltabbakh GH; Division of Gynecologic Oncology, University of Vermont, Burlington 05401, USA., Moody J, Garafano LL, Hammond JM
Jazyk: angličtina
Zdroj: European journal of gynaecological oncology [Eur J Gynaecol Oncol] 1999; Vol. 20 (1), pp. 18-9.
Abstrakt: Uterine papillary serous adenocarcinoma is an uncommon and very aggressive type of endometrial cancer. A 76-year-old patient diagnosed with recurrent uterine papillary serous adenocarcinoma was prescribed megesterol acetate (160 mg daily), paclitaxel (135 mg/m2) and carboplatin (area under the concentration-time curve of 5) every 4 weeks for 4 courses. She demonstrated complete clinical response that was maintained for longer than 6 months with minimal toxicity. The combination megesterol acetate, paclitaxel and carboplatin may be effective in women with recurrent uterine papillary serous adenocarcinoma.
Databáze: MEDLINE