Exfoliative cytology in screening for malignant and premalignant lesions in the buccal mucosa.
| Autor: | Ramaesh T; Department of Basic Sciences, Faculty of Dental Sciences, University of Peradeniya., Ratnatunga N, Mendis BR, Rajapaksa S |
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| Jazyk: | angličtina |
| Zdroj: | The Ceylon medical journal [Ceylon Med J] 1998 Dec; Vol. 43 (4), pp. 206-9. |
| Abstrakt: | Objective: To test the efficacy of exfoliative cytology in the detection of oral premalignant and malignant lesions. Design: Cytological diagnosis of lesions of the buccal mucosa assessed using histopathological diagnosis of the same lesions as the gold standard. Subjects: Patients with buccal lesions clinically diagnosed as leukoplakia (n = 91) and squamous cell carcinoma (SCC, n = 59), and healthy subjects (n = 40) in whom buccal mucosa appeared clinically normal. Setting: Oral and Maxillo-facial Unit, General Hospital, Kandy and Department of Pathology, Faculty of Medicine, University of Peradeniya. Results: A sensitivity of 77%, specificity of 100% and accuracy of 92% were obtained for leukoplakia. SCC gave a sensitivity of 94%, specificity of 100% and an accuracy of 95%. Conclusions: Oral exfoliative cytology is a useful method for detecting oral premalignant and malignant lesions. Anucleated squames in a smear is non-diagnostic. |
| Databáze: | MEDLINE |
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