Partial protection of Plasmodium falciparum-vaccinated Aotus trivirgatus against a challenge of a heterologous strain.

Autor: Siddiqui WA, Taylor DW, Kan SC, Kramer K, Richmond-Crum S
Jazyk: angličtina
Zdroj: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 1978 Nov; Vol. 27 (6), pp. 1277-8.
DOI: 10.4269/ajtmh.1978.27.1277
Abstrakt: Two Aotus trivirgatus griseimenbra monkeys which had been immunized with the merozoite-enriched FUP strain of Plasmodium falciparum were protected against a primary challenge with the homologous strain. The results described here show that these two monkeys were protected against a subsequent challenge with a heterologous strain (FVO) of P. falciparum. The unimmunized control monkey died of FVO infection by day 18.
Databáze: MEDLINE