| Autor: |
de Conto Cinier C; Chimie Analytique 2, LICAS, Université Claude Bernard Lyon 1, Villeurbanne, France., Petit-Ramel M, Faure R, Garin D, Bouvet Y |
| Jazyk: |
angličtina |
| Zdroj: |
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology [Comp Biochem Physiol C Pharmacol Toxicol Endocrinol] 1999 Mar; Vol. 122 (3), pp. 345-52. |
| DOI: |
10.1016/s0742-8413(98)10132-9 |
| Abstrakt: |
Carp (Cyprinus carpio) were tested for cadmium accumulation and elimination during and after a simulated pollution exposure. Fish were distributed in two 1000-l indoor concrete aquaria supplied with a continuous flow (8 l min(-1)) of well water. The cadmium concentration was maintained at 53 microg l(-1) in one aquarium and 443 microg l(-1) in the other aquarium for 127 days. The exposure phase was followed by a 43-day depuration period. The cadmium accumulation in liver, kidney and muscle was measured by means of ICP-MS. The data showed that cadmium exposure produces significant cadmium uptake in tissues. Cadmium concentrations increased sharply in kidney and liver, whereas the pollutant level in muscle was only significant after 106 days. After 127 days of Cd exposure (53 microg l(-1)), the cadmium concentration in kidney was 4-fold higher than in liver and 50-fold higher than in muscle for a toxic level of 53 microg l(-1). At a Cd of 443 microg l(-1), kidney cadmium content was 2-fold higher than in liver and 100-fold higher than in muscle. In kidney and liver, the toxic concentration increased as the concentration of pollutant in water increased. During the 43 depuration days, the loss of accumulated cadmium was rapid and immediate in muscle. Conversely, no loss of cadmium was observed in kidney and liver. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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