Autor: |
Freskos JN; Department of Medicinal Chemistry, Searle Discovery Research, St Louis, MO 63198, USA., Mischke BV, DeCrescenzo GA, Heintz R, Getman DP, Howard SC, Kishore NN, McDonald JJ, Munie GE, Rangwala S, Swearingen CA, Voliva C, Welsch DJ |
Jazyk: |
angličtina |
Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 1999 Apr 05; Vol. 9 (7), pp. 943-8. |
DOI: |
10.1016/s0960-894x(99)00116-x |
Abstrakt: |
We have discovered a new series of potent MMP Inhibitors that are selective for MMP-13 over MMP-1 incorporating a gamma-sulfone thiol. |
Databáze: |
MEDLINE |
Externí odkaz: |
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