Prostaglandin in the saliva of the cattle tick Boophilus microplus.

Autor: Dickinson RG, O'Hagan JE, Schotz M, Binnington KC, Hegarty MP
Jazyk: angličtina
Zdroj: The Australian journal of experimental biology and medical science [Aust J Exp Biol Med Sci] 1976 Oct; Vol. 54 (5), pp. 475-86.
DOI: 10.1038/icb.1976.48
Abstrakt: Previous studies of saliva from engorged female cattle ticks revealed a component which induced contration of some isolated smooth muscles. Fractionation and further characterisation have shown that this substance is of the "slow-reacting" type, but that it is neither a bradykinin nor slow-reacting substance of anaphylaxis. The substance is deactivated by incubation with 15-hydroxprostaglandin dehydrogenase and its pharmacological properties also support its classification as a prostaglandin. A second pharmacologically-active component has now been found in the saliva but has not yet been characterised.
Databáze: MEDLINE