Autor: |
Schwartz MW; Department of Medicine, University of Washington, Harborview-Medical Center and the VA Puget Sound Health Care System, Seattle 98108, USA. mschwart@u.washington.edu, Baskin DG, Kaiyala KJ, Woods SC |
Jazyk: |
angličtina |
Zdroj: |
The American journal of clinical nutrition [Am J Clin Nutr] 1999 Apr; Vol. 69 (4), pp. 584-96. |
DOI: |
10.1093/ajcn/69.4.584 |
Abstrakt: |
In 1995, we described a new model for adiposity regulation. Since then, data regarding the biology of body weight regulation has accumulated at a remarkable rate and has both modified and strengthened our understanding of this homeostatic system. In this review we integrate new information into a revised model for further understanding this important regulatory process. Our model of energy homeostasis proposes that long-term adiposity-related signals such as insulin and leptin influence the neuronal activity of central effector pathways that serve as controllers of energy balance. |
Databáze: |
MEDLINE |
Externí odkaz: |
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