| Autor: |
Gulaya NM; O.V. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine., Kuzmenko AI, Margitich VM, Govseeva NM, Melnichuk SD, Goridko TM, Zhukov AD |
| Jazyk: |
angličtina |
| Zdroj: |
Chemistry and physics of lipids [Chem Phys Lipids] 1998 Dec; Vol. 97 (1), pp. 49-54. |
| DOI: |
10.1016/s0009-3084(98)00093-0 |
| Abstrakt: |
Two long-chain N-acylethanolamines (NAEs), N-palmitoyl- (NPE) and N-stearoylethanolamine (NSE), are shown to inhibit an in vitro non-enzymatic Fe(2+)-induced free radical oxidation of lipids in the liver mitochondria of rats with hypoxic hypoxia. NSE appeared to be more effective than NPE in suppressing some kinetic parameters of the Fe(2+)-induced chemiluminescence. The inhibitory action of NAEs on non-enzymatic lipid peroxidation supports the idea that they possess membrane protective properties. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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