| Autor: |
Dichi I; Departamento de Clínica Médica, Universidade Estadual de Londrina, PR., Dichi JB, Frenhane P, Correa CR, Angeleli AY, Bicudo MH, Rodrigues MA, Victória CR, Burini RC |
| Jazyk: |
portugalština |
| Zdroj: |
Arquivos de gastroenterologia [Arq Gastroenterol] 1998 Jul-Sep; Vol. 35 (3), pp. 175-80. |
| Abstrakt: |
Disease activity was assessed in 10 (five males and five females) ulcerative colitis patients through the following parameters: clinical, laboratory, sigmoidoscopic and histological. Protein metabolism was also assessed with 15N-glycine and urinary ammonia as end product. Only one patient had exacerbation of the disease two months after the study started. This patient presented in the beginning of the study protein synthesis and breakdown of 4.51 and 3.47 g protein/kg/day, respectively, values higher than all other patients, showing an hypermetabolic state, suggesting an increase of the disease activity. However, this increase was not detected by others indicators and indexes utilized. These data allow to suggest the hypothesis that protein metabolism predicts precociously the exacerbation of disease activity in ulcerative colitis patients. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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