Abstrakt: |
Summary: This book explains the basic concepts necessary for adjusting dosing regimens, presents equations in a conceptual manner, and describes the steps required to adjust dosages when the recommended manufacturer's dose is inadequate. The equations are developed, not through lengthy derivations, but by taking an intuitive approach. They are presented in their conceptual form, rather than a separate convenient form applicable to each clinic situation. The author defines pertinent pharmacokinetic terms, kinetic processes, and classical modeling relevant to dosing adjustments. Examples are included that emphasize an understanding of the concepts. |