Abstrakt: |
Abstract: Several laboratories have been involved in the research of synaptic transmitters and receptors during the post-World War II period in Czechoslovakia. The main contributions concerned the role of acetylcholine in the heart, motor nerves, skeletal muscles and the intestine, the synthesis of acetylcholine in the nerve terminals and its release, the role of catecholamines and the sympathoadrenal system in stress, the function of adenylate cyclase and cyclic AMP, and the function of muscarinic acetylcholine receptors and N-methyl-D-aspartate (NMDA) receptors. It would be difficult to provide a complete review of the work performed; some of its most interesting aspects are only mentioned in the following text. |