| Abstrakt: |
Cellerant Therapeutics, Inc., a clinical-stage company developing innovative immunotherapies for hematologic malignancies and other blood-related disorders, presented results from its randomized controlled Phase 2 clinical trial of CLT-008 (romyelocel-L, human myeloid progenitor cells), an off-the-shelf cell therapy which does not require HLA matching intended to prevent bacterial and fungal infections during neutropenia. As part of the Phase 2 trial, CLT-008 was evaluated in newly diagnosed acute myeloid leukemia (AML) patients who underwent standard “7+3” (cytarabine and an anthracycline) induction chemotherapy. One of the major side effects of 7+3 and other myelosuppressive chemotherapies is neutropenia, which leaves patients at high risk of serious infections. Results from the Phase 2 study showed that CLT-008 reduced the incidence of serious infections by 73% and reduced hospital length of stay by three days in patients who received 7+3 chemotherapy. The data were presented on Saturday, June 16, at the European Hematology Association (EHA) 23rd Congress in Stockholm. [ABSTRACT FROM PUBLISHER] |
