A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase I.

Autor: Chia-Chun Yu1, Shiow-Lin Pan2, Shi-Wei Chao3, Shih-Ping Liu4, Jui-Ling Hsu1, Yu-Chen Yang5, Tsia-Kun Li5, Wei-Jan Huang3 wjhuang@tmu.edu.tw, Jih-Hwa Guh1 jhguh@ntu.edu.tw
Zdroj: Biochemical Pharmacology. Aug2014, Vol. 90 Issue 3, p320-330. 11p.
Databáze: Academic Search Ultimate
Externí odkaz: