Identification of 1-{2-[4-chloro-1′-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4′-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y1 antagonist as an antiplatelet agent.

Autor:	Jeon, Yoon T.1, Yang, Wu1 wu.yang@bms.com, Qiao, Jennifer X.1 jennifer.qiao@bms.com, Li, Ling1, Ruel, Rejean1, Thibeault, Carl1, Hiebert, Sheldon1, Wang, Tammy C.1, Wang, Yufeng1, Liu, Yajun1, Clark, Charles G.1, Wong, Henry S.1, Zhu, Juliang1, Wu, Dauh-Rurng1, Sun, Dawn1, Chen, Bang-Chi1, Mathur, Arvind1, Chacko, Silvi A.2, Malley, Mary2, Chen, Xue-Qing2
Zdroj:	Bioorganic & Medicinal Chemistry Letters. Mar2014, Vol. 24 Issue 5, p1294-1298. 5p.
Databáze:	Academic Search Ultimate
Externí odkaz:	Zobrazit plný text záznamu Full Text from ScienceDirect