Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity.

Autor: Nobuya Ishii1, Naoki Harada1, Joseph, Eric W.2, Kazuhiro Ohara1, Takaaki Miura1, Hiroshi Sakamoto1, Yutaka Matsuda1, Yasushi Tomii1, Yukako Tachibana-Kondo1, Hitoshi Iikura1, Toshihiro Aoki1, Nobuo Shimma1, Mikio Arisawa1, Yoshihiro Sowa3, Poulikakos, Poulikos I.2, Rosen, Neal2 rosenn@mskcc.org, Yuko Aoki1, Toshiyuki Sakai3
Zdroj: Cancer Research. Jul2013, Vol. 73 Issue 13, p4050-4060. 11p.
Databáze: Academic Search Ultimate