Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas.

Autor: Iglesias, Maite, Frontelo, Pilar, Gamallo, Carlos, Quintanilla, Miguel
Zdroj: Oncogene. 8/24/2000, Vol. 19 Issue 36, p4134. 12p.
Databáze: Academic Search Ultimate