In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death, and induction of FLIP by NF-κB is required to prevent it
| Autor: | Moujalled, D M1, Cook, W D2, Lluis, J M2, Khan, N R2, Ahmed, A U3, Callus, B A4, Vaux, D L1 |
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| Zdroj: | Cell Death & Differentiation. May2012, Vol. 19 Issue 5, p808-815. 8p. 4 Graphs. |
| Databáze: | Academic Search Ultimate |
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