Identification of the MEK1(F129L) Activating Mutation as a Potential Mechanism of Acquired Resistance to MEK Inhibition in Human Cancers Carrying the B-Raf V600E Mutation.

Autor: Huisheng Wang1, Daouti, Sherif1, Wen-hui Li1, Yang Wen2, Rizzo, Christine1, Higgins, Brian1, Packman, Kathryn1, Rosen, Neal3, Boylan, John F.1, Heimbrook, David1, Huifeng Niu1 huifeng.niu@roche.com
Zdroj: Cancer Research. Aug2011, Vol. 71 Issue 16, p5535-5545. 11p.
Databáze: Academic Search Ultimate