Crystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity.
| Autor: | Paulsen, Janet L.1, Bendel, Stephen D.1, Anderson, Amy C.1 amy.anderson@uconn.edu |
|---|---|
| Zdroj: | Chemical Biology & Drug Design. Oct2011, Vol. 78 Issue 4, p505-512. 8p. 5 Diagrams, 2 Charts. |
| Databáze: | Academic Search Ultimate |
| Externí odkaz: |
|