A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism.

Autor: Egelund, Rikke, Petersen, Torben E., Andreasen, Peter A.
Zdroj: European Journal of Biochemistry. Feb2001, Vol. 268 Issue 3, p673. 13p. 4 Black and White Photographs, 3 Diagrams, 2 Charts, 1 Graph.
Databáze: Academic Search Ultimate