Design of novel and potent cPLA2α inhibitors containing an α-methyl-2-ketothiazole as a metabolically stable serine trap

Autor: Mete, Antonio1 Antonio.Mete@Astrazeneca.com, Andrews, Glen2, Bernstein, Mike1, Connolly, Stephen1, Hartopp, Paul1, Jackson, Clive G.2, Lewis, Richard1, Martin, Iain3, Murray, David2, Riley, Rob3, Robinson, David H.1, Smith, Gill M.2, Wells, Edward2, Withnall, W. John1
Zdroj: Bioorganic & Medicinal Chemistry Letters. May2011, Vol. 21 Issue 10, p3128-3133. 6p.
Databáze: Academic Search Ultimate