A Leu to Ile but not Leu to Val change at HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+L74I enzyme and a replication competent virus.
| Autor: | Chunduri, HimaBindu1, Rimland, David2, Nurpeisov, Viktoria1, Crumpacker, Clyde S.3, Sharma, Prem L.1,4 plsharm@emory.edu |
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| Zdroj: | Virology Journal. 2011, Vol. 8 Issue 1, p33-44. 12p. 1 Black and White Photograph, 2 Charts, 4 Graphs. |
| Databáze: | Academic Search Ultimate |
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