Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance.

Autor: Tianjun Zhou1, Commodore, Lois1, Wei-Sheng Huang1, Yihan Wang1, Thomas, Mathew1, Keats, Jeff1, Qihong Xu1, Rivera, Victor M.1, Shakespeare, William C.1, Clackson, Tim1, Dalgarno, David C.1 dalgarno@ariad.com, Xiaotian Zhu1 zhux@ariad.com
Zdroj: Chemical Biology & Drug Design. Jan2011, Vol. 77 Issue 1, p1-11. 11p. 4 Diagrams, 2 Charts, 2 Graphs.
Databáze: Academic Search Ultimate