Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X3/P2X2/3 antagonist for the treatment of pain

Autor: Carter, David S.1 david.carter@roche.com, Alam, Muzaffar1, Cai, Haiying1, Dillon, Michael P.1, Ford, Anthony P.D.W.2, Gever, Joel R.2, Jahangir, Alam1, Lin, Clara1, Moore, Amy G.1, Wagner, Paul J.1, Zhai, Yansheng1
Zdroj: Bioorganic & Medicinal Chemistry Letters. Mar2009, Vol. 19 Issue 6, p1628-1631. 4p.
Databáze: Academic Search Ultimate