ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity.
| Autor: | Fuentealba, Rodrigo A.1 fuentealba_r@kids.wustl.edu, Barría, Maria Ines1 mibarria@bio.puc.cl, Lee, Jiyeon2 jleef@artsci.wustl.edu, Cam, Judy2 judy.cam@med.nyu.edu, Araya, Claudia1 claudix05@gmail.com, Escudero, Claudia A.3 caescude@uc.cl, Inestrosa, Nibaldo C.1 ninestrosa@bio.puc.cl, Bronfman, Francisca C.3 fbronfman@bio.puc.cl, Guojun Bu3 bu@kids.wustl.edu, Marzolo, Maria-Paz1 mmarzolo@bio.puc.cl |
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| Zdroj: | Molecular Neurodegeneration. 2007, Vol. 2, p14-19. 19p. 4 Diagrams, 6 Graphs. |
| Databáze: | Academic Search Ultimate |
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