The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells.
| Autor: | Cuiyan Xin1, Shuyu Ren1, Eberhardt, Wolfgang1, Pfeilschifter, Josef1, Huwiler, Andrea1 Huwiler@em.uni-frankfurt.de |
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| Zdroj: | British Journal of Pharmacology. Jan2006, Vol. 147 Issue 2, p164-174. 11p. |
| Databáze: | Academic Search Ultimate |
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