Trifluoromethyl group as a pharmacophore: Effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand

Autor: Betageri, Raj1 rbetager@rdg.boehringer-ingelheim.com, Zhang, Yan2, Zindell, Renee M.1, Kuzmich, Daniel1, Kirrane, Thomas M.1, Bentzien, Jörg1, Cardozo, Mario3, Capolino, Alison J.1, Fadra, Tazmeen N.1, Nelson, Richard M.1, Paw, Zofia4, Shih, Daw-Tsun5, Shih, Cheng-Kon4, Zuvela-Jelaska, Ljiljana5, Nabozny, Gerald5, Thomson, David S.1
Zdroj: Bioorganic & Medicinal Chemistry Letters. Nov2005, Vol. 15 Issue 21, p4761-4769. 9p.
Databáze: Academic Search Ultimate
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