Combining lapatinib (GW572016), a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases, with therapeutic anti-ErbB2 antibodies enhances apoptosis of ErbB2-overexpressing breast cancer cells.
| Autor: | Wenle Xia1, Gerard, Catherine M.2, Leihua Liu1, Baudson, Nathalie M.2, Ory, Thierry L.2, Spector, Neil L.1 Neil.L.Spector@gsk.com |
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| Zdroj: | Oncogene. 9/15/2005, Vol. 24 Issue 41, p6213-6221. 9p. 4 Diagrams. |
| Databáze: | Academic Search Ultimate |
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