CalDAG-GEFI acts as a guanine nucleotide exchange factor for LRRK2 to regulate LRRK2 function and neurodegeneration.

Autor: Qinfang Liu1, Bingxu Huang1, Guiberson, Noah Guy Lewis2,3, Shifan Chen1, Dong Zhu1, Gang Ma4, Xin-Ming Ma1, Crittenden, Jill R.5,6, Jianzhong Yu4, Graybiel, Ann M.5, Dawson, Ted M.2,3,7,8,9,10 tdawson@jhmi.edu, Dawson, Valina L.2,3,7,11 vdawson@jhmi.edu, Yulan Xiong1 yxiong@uchc.edu
Zdroj: Science Advances. 11/22/2024, Vol. 10 Issue 47, p1-17. 17p.
Databáze: Academic Search Ultimate