Octanol/water partition coefficients estimated using retention times in reverse-phase liquid chromatography and calculated in silico as one of the determinant factors for pharmacokinetic parameter estimations of general chemical substances.

Autor: Koichiro Adachi1, Makiko Shimizu1, Fumiaki Shono2, Kimito Funatsu2, Hiroshi Yamazaki1 hyamazak@ac.shoyaku.ac.jp
Zdroj: Journal of Toxicological Sciences. 2024, Vol. 49 Issue 4, p127-137. 11p.
Databáze: Academic Search Ultimate