Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation.

Autor: Jiahui Lu1,2, Peng Ge1,2, Sawaya, Michael R.1,2, Hughes, Michael P.3, Boyer, David R.1,2, Qin Cao4, Abskharon, Romany1,2, Caseio, Duilio1,2, Tayeb-Fligelman, Einav1,2, Eisenberg, David S.1,2 david@mbi.ucla.edu
Zdroj: Journal of Biological Chemistry. Feb2024, Vol. 300 Issue 2, p1-15. 15p.
Databáze: Academic Search Ultimate