Investigating Tacrolimus Disposition in Paediatric Patients with a Physiologically Based Pharmacokinetic Model Incorporating CYP3A4 Ontogeny, Mechanistic Absorption and Red Blood Cell Binding.

Autor: Van der Veken, Matthias1 (AUTHOR) matthias.vanderveken@kuleuven.be, Brouwers, Joachim1 (AUTHOR) joachim.brouwers@kuleuven.be, Ozbey, Agustos Cetin2 (AUTHOR) agustos.ozbey@roche.com, Umehara, Kenichi2 (AUTHOR) kenichi.umehara@roche.com, Stillhart, Cordula3 (AUTHOR) cordula.stillhart@roche.com, Knops, Noël4,5 (AUTHOR) noelknops@telenet.be, Augustijns, Patrick1 (AUTHOR) patrick.augustijns@kuleuven.be, Parrott, Neil John2 (AUTHOR) neil_john.parrott@roche.com
Zdroj: Pharmaceutics. Sep2023, Vol. 15 Issue 9, p2231. 21p.
Databáze: Academic Search Ultimate
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