A Comparative Study on the Lysosomal Cation Channel TMEM175 Using Automated Whole-Cell Patch-Clamp, Lysosomal Patch-Clamp, and Solid Supported Membrane-Based Electrophysiology: Functional Characterization and High-Throughput Screening Assay Development.

Autor: Bazzone, Andre1 (AUTHOR) andre.bazzone@nanion.de, Barthmes, Maria1 (AUTHOR) soren.friis@nanion.de, George, Cecilia1 (AUTHOR), Brinkwirth, Nina1 (AUTHOR), Zerlotti, Rocco1,2 (AUTHOR), Prinz, Valentin1 (AUTHOR), Cole, Kim1 (AUTHOR), Friis, Søren1 (AUTHOR), Dickson, Alexander3 (AUTHOR) alexander.dickson@sbdrugdiscovery.com, Rice, Simon3 (AUTHOR) simon.rice@sbdrugdiscovery.com, Lim, Jongwon4 (AUTHOR) jongwon.lim@cerevel.com, Fern Toh, May4 (AUTHOR) mayfern.toh@cerevel.com, Mohammadi, Milad5 (AUTHOR), Pau, Davide3 (AUTHOR), Stone, David J.4 (AUTHOR) david.stone@cerevel.com, Renger, John J.4 (AUTHOR) john.renger@cerevel.com, Fertig, Niels1 (AUTHOR) andre.bazzone@nanion.de
Zdroj: International Journal of Molecular Sciences. Aug2023, Vol. 24 Issue 16, p12788. 52p.
Databáze: Academic Search Ultimate
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