First‐in‐human trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of zagociguat (CY6463), a CNS‐penetrant soluble guanylyl cyclase stimulator.

Autor: van Kraaij, Sebastiaan J. W.1,2 (AUTHOR), Gal, Pim1,2 (AUTHOR), Borghans, Laura G. J. M.1 (AUTHOR), Klaassen, Erica S.1 (AUTHOR), Dijkstra, Francis1,2 (AUTHOR), Winrow, Christopher3 (AUTHOR), Glasser, Chad3 (AUTHOR), Groeneveld, Geert Jan1,2 (AUTHOR) ggroeneveld@chdr.nl
Zdroj: CTS: Clinical & Translational Science. Aug2023, Vol. 16 Issue 8, p1381-1395. 15p.
Databáze: Academic Search Ultimate
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